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Posts tagged "cholinergic"

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vagus nerve hashimotos thyroid

Hashimoto's, the Thyroid, and the Vagal Anti-Inflammatory Reflex

Hashimoto's is an autoimmune disease, and like all autoimmune diseases it lives or dies by the body's ability to resolve inflammation. The vagus nerve runs that resolution program — and its dysfunction is consistently observed in autoimmune thyroid disease.

By VagusSkool Team May 14, 2026

vagus nerve chronic pain central sensitization

Chronic Pain Is a Vagal Problem: How the Cholinergic Brake Counters Central Sensitization

Chronic pain is increasingly understood as a disorder of central sensitization driven by neuroinflammation — and the vagus nerve is one of the few systems with direct biological access to that loop.

By VagusSkool Team May 14, 2026

vagus nerve mcas mast cell

MCAS and the Vagal Brake: Why Mast Cells Need a Quiet Nervous System

Mast cells are wired into the autonomic nervous system. When the vagal brake fails, mast cells become reactive — and the cholinergic anti-inflammatory pathway emerges as one of the most underused tools in MCAS care.

By VagusSkool Team May 11, 2026

inflammation vagus nerve immune system

The Inflammatory Reflex: How the Vagus Nerve Controls Immune Balance

The vagus nerve’s cholinergic anti-inflammatory pathway is your body’s fastest mechanism for controlling inflammation — a neural circuit that could reshape how we treat chronic disease.

By VagusSkool Apr 9, 2026