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baroreflex pots orthostatic intolerance

The Baroreflex: The Blood-Pressure Thermostat the Vagus Runs — and What Breaks in POTS

Every time you stand, gravity yanks blood toward your feet and your blood pressure should drop — but usually it doesn't, because a reflex loop catches it within a single heartbeat. That loop is the baroreflex, and the vagus runs half of it. In POTS, the loop's gain is off, so instead of a smooth catch, your heart races.

By VagusSkool Team Jul 22, 2026

small fiber neuropathy skin biopsy long covid

Small Fiber Neuropathy and the Vagus: The Damage a Skin Biopsy Can Finally See

For years, people with burning pain, dizziness, and gut and heart symptoms were told the tests were normal and the problem was in their head. The tests were normal because they measured the wrong nerves. A simple skin biopsy measures the right ones — and can show, objectively, that the tiniest fibers are dying.

By VagusSkool Team Jul 22, 2026

vagus nerve pots dysautonomia

The Three Faces of POTS: A Clinical Map of Hyperadrenergic, Neuropathic, and Hypovolemic Subtypes

POTS is one diagnosis with at least three distinct physiologies. Treating them as one condition is one of the most common reasons patients stay sick. The subtype determines the protocol.

By VagusSkool Team May 14, 2026

vagus nerve eds hypermobility

The Hypermobility Trifecta: hEDS, POTS, and MCAS — Why the Vagus Nerve Is the Bridge

Hypermobile EDS, POTS, and MCAS travel together in a way that purely structural or purely immune models cannot explain. The bridge that ties all three together is autonomic — and the vagus nerve is the central player.

By VagusSkool Team May 11, 2026

vagus nerve long covid autonomic dysfunction

Long COVID and the Damaged Vagus: A Three-Reflex Model of Recovery

A 2024 mechanistic framework reframes Long COVID as a coordinated failure of three anti-inflammatory reflexes — vagal, HPA, and mitochondrial — and explains why some patients improve only when treatment addresses all three together.

By VagusSkool Team May 11, 2026